Protein Details: Aquaporin Lacbi1:391485

Protein ID

ICDB_Pro_0079

Protein Name

Aquaporin Lacbi1:391485

Gene Name

Lacbi1:391485; LACBIDRAFT_252507

Organism

Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver) (Laccaria laccata var. bicolor)

Length

312 amino acids

AlphaFoldDB

AF-B0DLE4-F1-model_v4.pdb

Function

Water channel required to facilitate the transport of water across membranes . In addition to water; shows also strong glycerol and ammonium transport activities . May be involved in fungal nitrogen (ammonium) support of the plant host in symbiosis . Glycerol accumulation has never been observed in ectomycorrhizal (ECM) fungi; therefore; glycerol permeability of Lacbi1:391485 might be a relict of the affiliation of the protein to the group of aquaglyceroporins; and other osmotic active compounds (e.g. trehalose or mannitol) may have taken over glycerol function in ECM fungi (Probable).

Sequence

MDDKFDDDALPNSKTTPEDYGDKLAEYDYTNTFPNTWMRLREPFREYIAEFVGVAVLIIFGVGADCQVVLSANTGVAPSPKGDYLSLNCGWAIGTAMGVWISGGISGGHINPAVTLALMAWRGFPWWKVPGFIFAQLLGGIVGAGLVYVNYIHAIDIVEGGRHIRTLDTAGLFATYAADYMTNVSCFFSEFLATAVLIVVIHAMNDKRNAPPPAGLAPLVLFFLILGIGASLGMETGYAINPARDLGPRMLTAMVGYGRQVFAFRNQYWIWCPVIAPFLGAQVGTIFYDLFFYKGQDNVFGRLGSHIHISPA

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1038/nature06556; 10.1111/j.1469-8137.2011.03651.x

RefSeq

XP_001884805.1

Feature